Search results for "Cross linker"
showing 4 items of 4 documents
Synthesis and Characterization of Base Labile Poly(N-isopropylacrylamide) Networks Utilizing a Reactive Cross-Linker
2008
A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis
2015
International audience; The variety of protein cross-linkers developed in recent years illustrates the current requirement for efficient reagents optimized for mass spectrometry (MS) analysis. To date, the most widely used strategy relies on commercial cross-linkers that bear an isotopically labeled tag and N-hydroxysuccinimid-ester (NHS-ester) moieties. Moreover, an enrichment step using liquid chromatography is usually performed after enzymatic digestion of the cross-linked proteins. Unfortunately, this approach suffers from several limitations. First, it requires large amounts of proteins. Second, NHS-ester cross-linkers are poorly efficient because of their fast hydrolysis in water. Fin…
A New Type of Artificial Oxygen Carrier: Soluble Hyperpolymeric Haemoglobin with Negligible Oncotic Pressure—Production of Thermally Stable Hyperpoly…
1992
A two-step synthesis of new macrobicyclic aza-ligands starting from “trans”dioxocyclam as diprotected macrocycle
1997
Abstract A rapid and convenient synthesis of two small aza-cryptands containing a 1,4,8,11-tetraazacyclotetradecane backbone is reported. This strategy can be applied to the preparation of many other aza-cages by varying the nature of the cross linker. Moreover, the two remaining secondary amine sites may allow the functionalization of these ligands or their grafting on a polymer.